Helen Swede, Ph.D.

• Cancer Epidemiologist at the Connecticut Tumor Registry, a part of the Surveillance, Epidemiology, and End Results (SEER) program of the National Cancer Institute  
• Post-doctoral fellowship in molecular epidemiology at the Roswell Park Cancer Institute
• Pre-doctoral fellowship from National Cancer Institute while at Roswell Park Cancer Institute and University at Buffalo 
• Young Investigator Scholar Award from the American Association of Cancer Research (2000)
• Graduate Student Research Prize, New York State Public Health Association (1999)
• Research and development at the Xerox Corporation and Eastman Kodak Company

Research Interests

I am investigating the link between insulin resistance and cancer.  Insulin resistance can result from being overweight or obese, which are serious public health problems confronting the United States today.  Excess weight, particularly central fat, can result in impaired glucose uptake by cells, and, subsequently, high levels of glucose and insulin circulating in the bloodstream.  One of the many effects of these excess levels is promotion of oxidative stress and inflammation, and resultant physiologic, cellular, and genetic damage.

Selected Publications

Stevens RG, Swede H , Levine J, Rosenberg DW.  Epidemiology of colonic aberrant crypt foci in a high-risk population. Cancer Lett. 2007 Apr 18;248(2):262-8. Epub 2006 Sep 6.

Stevens RG, Swede H , Rosenberg DW.  Epidemiology of aberrant crypt foci:  Review of existing studies. Cancer Lett. 2007 Jul 18;252(2):171-83. Epub 2006 Dec 19.

Swede H , Cheng N, Bartos J, Shaukat A, Stoler D, Rodriguez-Bigas M, Natarajan R, Petrelli NJ, Cummings KM, Anderson GR. Cigarette smoking and genomic instability in sporadic colorectal cancer. Cancer Genet Cytogenet. 2006 Jul 15; 168(2):98-104.

Stoler DL, Bartos JD, Swede H , Edge SB, Winston JS, Wiseman SM, Anderson GR. Genomic instability in invasive breast carcinoma measured by Inter-Simple Sequence Repeat PCR. Breast Cancer Res Treat. 2006 May; 97(1):107-10.

Menezes RJ, Swede H , Moysich KB. Association of regular aspirin use and prostate cancer. Cancer Causes Control. 2006 Apr; 17(3):251-6.

Swede H , Mirand AL, Menezes RJ, Moysich KB. Association of regular aspirin use and breast cancer. Oncology. 2005; 68:39-46.

Swede H , Dong Y, Reid M, Marshall J, Ip C. Cell cycle arrest biomarkers in human lung cancer cells after treatment with selenium in culture. Cancer Epidem, Biom & Prev. 2003; 12:1248-1252.

Wiseman SM, Swede H , Stoler DL, Anderson GR, Hicks WL, Rigual NR, Tan D, Loree TR. Squamous cell carcinoma of head and neck in non-smokers and non-drinkers. Annals of Surg Oncol. 2003; 10(5):551-557.

Swede H , Moysich KB, Winston JS, Hurd TC, Edge SB, Romero-Gutierrez M, Brooks JSJ, Michalek AM. Variation of prognostic significance of HER2 expression in breast cancer according to tumor size. Breast J. 2003; 9(2):99-106.

Swede H , Moysich KB, Michalek AM, Freudenheim JL, Quirk JT, Winston JS, Hurd TC, Edge SE, Muti PC. Breast cancer risk factors and HER2 overexpression in tumors. Cancer Prev Detect. 2001; 25(6):511-519.

Anderson GR, Brenner BM, Swede H , Henry M, Conroy J, Karpendo M, Issa JP, Chen N, Jahreis G, Kahlenberg M, Basik, M, Rodriguez-Bigas M, Nowak N, Petrelli NJ, Shows TB and Stoler DL. Cooperating loci associated with genomic instability in human sporadic colorectal cancer. Cancer Res. 2001; 61(22): 8274-8283.

Contact Information

Division of Epidemiology and Biostatistics
Department of Community Medicine and Health Care
University of Connecticut School of Medicine
263 Farmington Avenue, MC 6325
Farmington, CT 06030-6325
Phone: (860) 679-5568
Fax: (860) 679-1581
Email: hswede@uchc.edu

Helen Swede, Ph.D.

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